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Initial Design & Agent Roles
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Linked challenge: MCP-Enabled Drug Design Agent
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Linked challenge
MCP-Enabled Drug Design Agent
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Original prompt text with formatting preserved for inspection.
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Design the overall LangGraph workflow for autonomous scientific design. Define the primary agents (e.g., Researcher, HypothesisGenerator, SimulationAnalyst, RefinementAgent) and their roles. Outline how 'extended thinking' with adaptive reasoning budgets will be integrated into the HypothesisGenerator using GPT-5. Specify the communication flow and state transitions.
Adaptation plan
Keep the source stable, then change the prompt in a predictable order so the next run is easier to evaluate.
Keep stable
Preserve the role framing, objective, and reporting structure so comparison runs stay coherent.
Tune next
Swap in your own domain constraints, anomaly thresholds, and examples before you branch variants.
Verify after
Check whether the prompt asks for the right evidence, confidence signal, and escalation path.