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Write PySAM PCR Leaping Artifact Detector
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Linked challenge: Bacterial Gene Screening PCR Leaping Artifact Filter with PySAM
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Linked challenge
Bacterial Gene Screening PCR Leaping Artifact Filter with PySAM
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Write a Python script using `pysam` to inspect read alignment records and filter reads exhibiting PCR template leaping motifs.
Adaptation plan
Keep the source stable, then change the prompt in a predictable order so the next run is easier to evaluate.
Keep stable
Hold the task contract and output shape stable so generated implementations remain comparable.
Tune next
Update libraries, interfaces, and environment assumptions to match the stack you actually run.
Verify after
Test failure handling, edge cases, and any code paths that depend on hidden context or secrets.