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Initialize OpenAI Agents SDK Variant Classifier
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Linked challenge: Missense Variant Triage Agent with OpenAI Agents SDK and Google Jules
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Linked challenge
Missense Variant Triage Agent with OpenAI Agents SDK and Google Jules
Prompt source
Original prompt text with formatting preserved for inspection.
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Write a Python script using `openai_agents` that defines a VariantClassifier agent. The agent should expose custom tools built on Biopython to fetch ClinVar entries and calculate missense impact scores.
Adaptation plan
Keep the source stable, then change the prompt in a predictable order so the next run is easier to evaluate.
Keep stable
Hold the task contract and output shape stable so generated implementations remain comparable.
Tune next
Update libraries, interfaces, and environment assumptions to match the stack you actually run.
Verify after
Test failure handling, edge cases, and any code paths that depend on hidden context or secrets.