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Challenge

Prior-Authorization Oncology Review Agent using LangChain and Llama 3.3 70B

Processing oncology prior-authorization requests demands aligning patient gene mutant dosage against metastatic tropism evidence. Build a stateful LangChain and LangGraph pipeline powered by Llama 3.3 70B to evaluate unstructured clinical records and yield structured approval determinations with 90% precision.

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Challenge brief

What you are building

The core problem, expected build, and operating context for this challenge.

Build an enterprise oncology prior-authorization agent using LangChain, LangGraph, and Llama 3.3 70B.

Delivery guide

How work is evaluated

Evaluation

Evaluates precision and evidence extraction accuracy of prior-authorization determinations.

Datasets

Challenge datasets

Public datasets, plus the private datasets you have access to.

Evaluation rubric

How submissions are scored

These dimensions define what the evaluator checks and which criteria separate a passable run from a strong one.

Dimensions
2 scoring checks
Binary
2 pass or fail dimensions
Ordinal
0 scaled dimensions
Dimension 1

decision_validity

Checks if decision is strictly APPROVED or DENIED.

Binary check

This dimension contributes its full weight only when the submission satisfies the requirement. Partial credit is not awarded.

Dimension 2

decision_precision

Precision of approval determinations against expert oncologist consensus. • target: 0.9 • range: 0-1

Binary check

This dimension contributes its full weight only when the submission satisfies the requirement. Partial credit is not awarded.

Learning goals

What you should walk away with

  • Design stateful multi-step graphs using LangChain and LangGraph.

  • Integrate Llama 3.3 70B for clinical record processing and reasoning.

  • Parse unstructured medical records and cross-reference gene mutant dosage data.

  • Output standardized JSON prior-authorization decisions with evidence citations.

Resources and assets

Reference links and supporting material

Dataset notes

De-identified synthetic prior-authorization requests combining clinical oncology progress notes with genomic sequencing reports.

Challenge setup

Evaluates precision and evidence extraction accuracy of prior-authorization determinations.

Challenge input

JSON containing patient clinical text, targeted drug, and genomic mutation profile.

LangChain

Industry standard framework for building retrieval and tool-augmented chains.

Llama 3.3 70B

High-capacity open weights model for complex clinical text reasoning.

Evaluated output

JSON with decision (APPROVED/DENIED), rationale, and cited_evidence.

Evaluation checks
  • Checks if decision is strictly APPROVED or DENIED.
  • Precision of approval determinations against expert oncologist consensus. • target: 0.9 • range: 0-1
Configured evaluation evidence
  • Benchmark: Clinical Prior-Authorization Benchmark
  • Decision Precision target: 0.9
  • 1 public reference case
Configured runtime
  • Python execution harness
  • Python sandbox (unavailable on Versalist)

Summary shows the first task, up to three tools, and up to three evidence items. Open the technical recipe to view all configured items.

View technical recipe

Configured tools

Action Space
  • Llama 3.3 70B · Required
  • Langchain · Optional
  • Stainless · Optional
Orchestration
  • Langchain · Optional

Evaluation contract

  • decision_validity · Weight 1
  • decision_precision · Weight 1

Metrics

  • decision_precision · Target 0.9

Benchmarks

  • Clinical Prior-Authorization Benchmark
  • biotech

Reference cases

  • 1 public reference case

Workflow tasks

  1. Task 1

    Input: JSON containing patient clinical text, targeted drug, and genomic mutation profile.

    Output: JSON with decision (APPROVED/DENIED), rationale, and cited_evidence.

    Execution harness: Python

Evaluation tools

  • LangChain · Agent Framework
  • Llama 3.3 70B · LLM Engine

Recipe freeze marker

No recipe freeze time is recorded.

Frequently Asked Questions about Prior-Authorization Oncology Review Agent using LangChain and Llama 3.3 70B