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Challenge

Genomic Patent Prior Art and Infringement Classifier with AutoGen

IP disputes in single-cell sequencing require rigorous multi-agent analysis of patent claims against scientific publications. Build a conversational multi-agent audit team using Microsoft AutoGen to parse claim charts and highlight overlapping method steps. Achieve 90% precision on patent claim overlap extraction.

Data ScienceHosted by Vera
Challenge brief

What you are building

The core problem, expected build, and operating context for this challenge.

Orchestrate a multi-agent patent audit system using Microsoft AutoGen to evaluate genomic tech claims against prior art.

Delivery guide

How work is evaluated

Evaluation

Evaluates accuracy in detecting matching elements between single-cell patent claims and prior art protocols.

Datasets

Challenge datasets

Public datasets, plus the private datasets you have access to.

Evaluation rubric

How submissions are scored

These dimensions define what the evaluator checks and which criteria separate a passable run from a strong one.

Dimensions
2 scoring checks
Binary
2 pass or fail dimensions
Ordinal
0 scaled dimensions
Dimension 1

risk_level_format

Risk level must be HIGH, MEDIUM, or LOW.

Binary check

This dimension contributes its full weight only when the submission satisfies the requirement. Partial credit is not awarded.

Dimension 2

claim_overlap_precision

Precision of identified claim limitations matching prior art text • target: 0.9 • range: 0-1

Binary check

This dimension contributes its full weight only when the submission satisfies the requirement. Partial credit is not awarded.

Learning goals

What you should walk away with

  • Implement multi-agent conversation topologies using Microsoft AutoGen framework

  • Extract structured patent claim elements from USPTO documentation

  • Cross-examine genomic library preparation protocol steps against prior art literature

  • Generate evidence reports highlighting potential claim infringement and anticipation risks

Resources and assets

Reference links and supporting material

Dataset notes

Dataset of 50 paired single-cell RNA-seq patent claims (e.g. 10x Genomics vs Parse) and corresponding research paper methods.

Challenge setup

Evaluates accuracy in detecting matching elements between single-cell patent claims and prior art protocols.

Challenge input

JSON containing patent_claim_text and prior_art_method_text.

AutoGen

Framework specified for multi-agent group chat consensus.

Evaluated output

JSON object with overlapping_elements array, infringement_risk_level, and consensus_reasoning.

Evaluation checks
  • Risk level must be HIGH, MEDIUM, or LOW.
  • Precision of identified claim limitations matching prior art text • target: 0.9 • range: 0-1
Configured evaluation evidence
  • Benchmark: Biotech Patent Claim Infringement Benchmark
  • Claim Overlap Precision target: 0.9
  • 1 public reference case
Configured runtime
  • Python execution harness
  • Python sandbox (unavailable on Versalist)

Summary shows the first task, up to three tools, and up to three evidence items. Open the technical recipe to view all configured items.

View technical recipe

Configured tools

Action Space
  • AutoGen · Required
  • HeyBoss AI · Optional
  • Qwen2.5-72B · Optional

Evaluation contract

  • risk_level_format · Weight 1
  • claim_overlap_precision · Weight 1

Metrics

  • claim_overlap_precision · Target 0.9

Benchmarks

  • Biotech Patent Claim Infringement Benchmark
  • biotech

Reference cases

  • 1 public reference case

Workflow tasks

  1. Task 1

    Input: JSON containing patent_claim_text and prior_art_method_text.

    Output: JSON object with overlapping_elements array, infringement_risk_level, and consensus_reasoning.

    Execution harness: Python

Evaluation tools

  • AutoGen · Multi-agent Conversational Framework

Recipe freeze marker

No recipe freeze time is recorded.

Frequently Asked Questions about Genomic Patent Prior Art and Infringement Classifier with AutoGen