Skip to main content
Challenge

Build a FHIR ResearchStudy and Molecular Observation Bundle Orchestrator

Construct multi-resource FHIR R5 bundles linking ResearchStudy, Specimen, and DiagnosticReport entities. Validate cross-resource references and export bundles for translational biobanks.

Data ScienceHosted by Vera
Challenge brief

What you are building

The core problem, expected build, and operating context for this challenge.

Construct multi-resource FHIR R5 bundles linking ResearchStudy, Specimen, and DiagnosticReport entities. Validate cross-resource references and export bundles for translational biobanks.

Interoperability Architect

Ingest trial metadata and synthetic sequence observation tables.

Construct corresponding FHIR ResearchStudy and Observation resources with valid references.

Evaluate link integrity between specimens and molecular diagnostic reports.

Serialize bundle into standard FHIR R5 JSON format with narrative sections.

Web interface with visual resource dependency graph and JSON schema validator.

Construct synthetic research trial protocols and synthetic specimen IDs matching FHIR R5 schema guides. Starter examples below are synthetic. They are not downloaded records.

HL7 FHIR overview Implements FHIR resource composition and reference linking between Foundation, Administration, and Diagnostics modules.

langgraph, pydantic, fastapi. LangGraph manages stateful multi-step cycles required to resolve and validate bi-directional FHIR references. API-hosted Claude or OpenAI model to verify narrative text consistency and FHIR rule alignment.

Submit runnable source, pinned dependencies, setup commands, a working interface, example outputs, and a recorded end-to-end demo. Include tests and an action log.

Builds valid FHIR R5 Bundle objects containing ResearchStudy and Specimen resources.

Ensures all internal resource references resolve without broken pointers.

Validates resource syntax against standard FHIR JSON schemas.

```json [ { "input": { "study_id": "STUDY-42", "title": "Synthetic Genomic Trial", "specimen_ids": [ "SP-10" ] }, "expected_output": { "resourceType": "Bundle", "type": "collection", "total_resources": 2, "reference_integrity": "VALID", "study_id": "STUDY-42" } }, { "input": { "study_id": "STUDY-43", "title": "Incomplete Trial", "specimen_ids": [ "SP-999_NONEXISTENT" ] }, "expected_output": { "resourceType": "Bundle", "type": "collection", "total_resources": 1, "reference_integrity": "BROKEN_REFERENCE", "missing_references": [ "SP-999_NONEXISTENT" ] } } ] ```

Translational research bundling engine using mock patient and study data. No diagnostic operations. Use mock external writes. Require human review before any real deployment.

Rules

Participation guide

Translational research bundling engine using mock patient and study data. No diagnostic operations. Use mock external writes and human review.

Delivery guide

How work is evaluated

Evaluation

Builds valid FHIR R5 Bundle objects containing ResearchStudy and Specimen resources. Ensures all internal resource references resolve without broken pointers. Validates resource syntax against standard FHIR JSON schemas.

Submission format

Runnable source, pinned dependencies, setup commands, working interface, example outputs, recorded demo, tests, and action logs.

Datasets

Challenge datasets

Public datasets, plus the private datasets you have access to.

Evaluation rubric

How submissions are scored

These dimensions define what the evaluator checks and which criteria separate a passable run from a strong one.

Dimensions
4 scoring checks
Binary
1 pass or fail dimensions
Ordinal
3 scaled dimensions
Dimension 1

Complete workflow

Ingest trial metadata and synthetic sequence observation tables. Construct corresponding FHIR ResearchStudy and Observation resources with valid references. Evaluate link integrity between specimens and molecular diagnostic reports. Serialize bundle into standard FHIR R5 JSON format with narrative sections.

Score scale
012
Score 0

Missing or incorrect.

Score 1

Partly complete, with documented gaps.

Score 2

Complete, with reproducible evidence.

Dimension 2

Correctness and evidence

Builds valid FHIR R5 Bundle objects containing ResearchStudy and Specimen resources. Ensures all internal resource references resolve without broken pointers. Validates resource syntax against standard FHIR JSON schemas.

Score scale
012
Score 0

Missing or incorrect.

Score 1

Partly complete, with documented gaps.

Score 2

Complete, with reproducible evidence.

Dimension 3

Review interface

Web interface with visual resource dependency graph and JSON schema validator.

Score scale
012
Score 0

Missing or incorrect.

Score 1

Partly complete, with documented gaps.

Score 2

Complete, with reproducible evidence.

Dimension 4

Safe execution

Translational research bundling engine using mock patient and study data. No diagnostic operations.

Binary check

This dimension contributes its full weight only when the submission satisfies the requirement. Partial credit is not awarded.

Learning goals

What you should walk away with

  • Ingest trial metadata and synthetic sequence observation tables.

  • Construct corresponding FHIR ResearchStudy and Observation resources with valid references.

  • Evaluate link integrity between specimens and molecular diagnostic reports.

  • Serialize bundle into standard FHIR R5 JSON format with narrative sections.

Resources and assets

Reference links and supporting material

Dataset notes

Construct synthetic research trial protocols and synthetic specimen IDs matching FHIR R5 schema guides. Supplied starter examples are synthetic, not source extracts.

Challenge setup

Configuration summary for this challenge.

Challenge input

Input details are not configured.

LangGraph

Runtime for stateful agent workflows.

Evaluated output

No output checks are configured.

Evaluation checks
  • Ingest trial metadata and synthetic sequence observation tables. Construct corresponding FHIR ResearchStudy...
  • Builds valid FHIR R5 Bundle objects containing ResearchStudy and Specimen resources. Ensures all internal r...
  • Web interface with visual resource dependency graph and JSON schema validator.
Configured evaluation evidence
  • 2 public reference cases
Configured runtime
  • 2 configured tools

Summary shows the first task, up to three tools, and up to three evidence items. Open the technical recipe to view all configured items.

View technical recipe

Configured tools

Action Space
  • LangGraph · Optional
Orchestration
  • LangGraph · Optional

Evaluation contract

  • Complete workflow · Weight 40
  • Correctness and evidence · Weight 30
  • Review interface · Weight 20
  • Safe execution · Weight 10

Reference cases

  • 2 public reference cases

Workflow tasks

No workflow tasks are configured.

Recipe freeze marker

No recipe freeze time is recorded.

Frequently Asked Questions about Build a FHIR ResearchStudy and Molecular Observation Bundle Orchestrator